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. Author manuscript; available in PMC: 2008 Oct 15.
Published in final edited form as: Neuroimage. 2007 Jul 18;38(1):34–42. doi: 10.1016/j.neuroimage.2007.06.032

Table 2.

Brain Regions Correlated with Seizure Severity

wt Brain Region Max t Avg t
Positive Hippocampus 14.77 6.44
Septum† 9.31 1.33
Thalamus 13.30 5.12
Midbrain 7.55 0.79
Olfactory Bulb 0.00 0.00
Cerebellum* 9.78 0.31
tPA-/- Brain Region Max t Avg t
Positive Hippocampus 14.58 5.91
Septum† 5.17 0.19
Thalamus 14.71 1.90
Midbrain 10.55 2.66
Olfactory Bulb 6.18 0.27
Cerebellum 12.97 0.85

Significant (p<0.001 corrected, or * p<0.002 corrected) clusters resulting from a voxel-wise correlation between brain activity and seizure severity for wt and tPA-/- mice. Anatomical definitions of the clusters were made based on the mouse atlas (Paxinos & Franklin, 2001). Data presented include the maximum t-value within the region (same for all significance levels) and the average t value within the region (at p<0.001) presented as an average of the left and right hemisphere.

†

Structure below the resolution of microPET.