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. 1990 Jan;172(1):498–500. doi: 10.1128/jb.172.1.498-500.1990

In vitro peptidoglycan synthesis by envelopes from Escherichia coli tolM mutants is inhibited by colicin M.

R E Harkness 1, V Braun 1
PMCID: PMC208462  PMID: 2152914

Abstract

An in vitro peptidoglycan synthesis reaction was employed to further characterize the role of the tolM product in colicin M-induced inhibition of peptidoglycan synthesis. It was found that the tolM product is not the colicin M target and that this gene product does not play a role in the interaction of the colicin with its target. Colicin M remained associated with envelopes prepared from colicin-treated tolM mutants. These findings suggested that the tolM product most likely is involved with the internalization of colicin M.

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Selected References

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