Abstract
The ampicillin-induced lysis of amino acid-deprived relA+ Escherichia coli was dissociated into two separate stages. The early stage ("priming") requiring the presence of ampicillin apparently involved the interaction of ampicillin with a target penicillin-binding protein. The later stage ("lysis induction") was ampicillin independent and required only chloramphenicol to relax the RelA-dependent control of peptidoglycan hydrolase activity.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cortay J. C., Cozzone A. J. Effects of aminoglycoside antibiotics on the coupling of protein and RNA syntheses in Escherichia coli. Biochem Biophys Res Commun. 1983 May 16;112(3):801–808. doi: 10.1016/0006-291x(83)91688-1. [DOI] [PubMed] [Google Scholar]
- Goodell W., Tomasz A. Alteration of Escherichia coli murein during amino acid starvation. J Bacteriol. 1980 Dec;144(3):1009–1016. doi: 10.1128/jb.144.3.1009-1016.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ishiguro E. E., Mirelman D., Harkness R. E. Regulation of the terminal steps in peptidoglycan biosynthesis in ether-treated cells of Escherichia coli. FEBS Lett. 1980 Nov 3;120(2):175–178. doi: 10.1016/0014-5793(80)80291-2. [DOI] [PubMed] [Google Scholar]
- Ishiguro E. E., Ramey W. D. Stringent control of peptidoglycan biosynthesis in Escherichia coli K-12. J Bacteriol. 1976 Sep;127(3):1119–1126. doi: 10.1128/jb.127.3.1119-1126.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kusser W., Ishiguro E. E. Involvement of the relA gene in the autolysis of Escherichia coli induced by inhibitors of peptidoglycan biosynthesis. J Bacteriol. 1985 Nov;164(2):861–865. doi: 10.1128/jb.164.2.861-865.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kusser W., Ishiguro E. E. Lysis of nongrowing Escherichia coli by combinations of beta-lactam antibiotics and inhibitors of ribosome function. Antimicrob Agents Chemother. 1986 Mar;29(3):451–455. doi: 10.1128/aac.29.3.451. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kusser W., Pisabarro A. G., De Pedro M. A., Ishiguro E. E. Decay of the ampicillin-induced lysis process in amino acid-deprived Escherichia coli. Antimicrob Agents Chemother. 1990 Jan;34(1):164–166. doi: 10.1128/aac.34.1.164. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Spratt B. G. Properties of the penicillin-binding proteins of Escherichia coli K12,. Eur J Biochem. 1977 Jan;72(2):341–352. doi: 10.1111/j.1432-1033.1977.tb11258.x. [DOI] [PubMed] [Google Scholar]
- Talbot M. K., Schaefer F., Brocks V., Christenson J. G. Reactivation of peptidoglycan synthesis in ether-permeabilized Escherichia coli after inhibition by beta-lactam antibiotics. Antimicrob Agents Chemother. 1989 Dec;33(12):2101–2108. doi: 10.1128/aac.33.12.2101. [DOI] [PMC free article] [PubMed] [Google Scholar]