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. 1991 Nov;173(22):7213–7218. doi: 10.1128/jb.173.22.7213-7218.1991

Site-specific methylation of 16S rRNA caused by pct, a pactamycin resistance determinant from the producing organism, Streptomyces pactum.

J P Ballesta 1, E Cundliffe 1
PMCID: PMC209227  PMID: 1657884

Abstract

Ribosomal resistance to pactamycin in clones of Streptomyces lividans containing DNA (pct) from Streptomyces pactum, the pactamycin producer, involves methylation of 16S RNA. The modified residue A-941 in S. lividans 16S rRNA (A-964 in the homologous Escherichia coli sequence) is converted to 1-methyladenosine, and the ribosomal ability to bind pactamycin is reduced or abolished.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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