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. 2007 Nov;56(11):1635–1636. doi: 10.1136/gut.2007.132522

A patient with impaired gastric motility

P A Paine 1,2,3,4, W Rees 1,2,3,4, C Babbs 1,2,3,4, J L Shaffer 1,2,3,4, G Armstrong 1,2,3,4, H Burnett 1,2,3,4, Q Aziz 1,2,3,4
PMCID: PMC2095635  PMID: 17938436

This is an introduction to the Gut tutorial “A patient with impaired gastric motility” hosted on BMJ Learning—the best available learning website for medical professionals from the BMJ Group.

The functional as opposed to inflammatory effects of gastrointestinal pathology are often neglected by clinicians. Helicobacter pylori infection may impair gastric function either due to the oedema associated with antral gastritis leading to gastric outlet obstruction or due to gastroparesis caused by release of inflammatory and immune mediators. Use of Giemsa stains alongside H & E and concurrent urease test increases the yield of H pylori when the clinical suspicion is strong. Gastric outlet obstruction due to H pylori infection is usually associated with peptic ulceration and narrowing of the pylorus or duodenum and eradication therapy can be an effective treatment. However, the evidence for an association between H pylori infection and impaired gastric motor function is conflicting. As malignancy is the most common cause of gastric outlet obstruction, combination of CT scan and endoscopic ultrasound would help in establishing the aetiology. In the absence of evident ulceration or an alternative explanation, however, H pylori infection can be considered as a cause of gastric outlet obstruction.

To access the tutorial (Interactive Case History), click on “BMJ Learning: Take this module” on BMJ Learning from the content box at the top right and bottom left of the online article. For more information please go to: http://gut.bmj.com/tutorials/collection.dtl

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