Table 3 Indications and contraindications for endoscopic resection in early squamous cell and Barrett's cancer.

	Indication for ER	Intermediate indication*	Contraindication for ER
Barrett's neoplasia	LGIN, HGIN, carcinoma, size <20 mm, no risk factors†, macroscopic type I, IIa, b, c	Adenocarcinoma >20 mm, multifocal adenocarcinoma, sm1 infiltration without risk factors	Sm2 tumour infiltration and deeper, sm1 cancer with one risk factor†, macroscopic type III
Squamous cell neoplasia	LGIN, HGIN, mucosal cancer, no risk factors†, macroscopic type I, IIa, b, c	Size >20 mm, multifocal cancer	Sm1 cancer and deeper, macroscopic type III

LGIN, Low‐grade intraepithelial neoplasia; HGIN, high‐grade intraepithelial neoplasia.

*Endoscopic resection (ER) should only be performed in highly experienced centres or under study conditions.

^†Risk factors: lymph vessel invasion (L1), venous infiltration (V1), poorly differentiated carcinoma (G3).