Table 3 Diagnostic accuracy in distinguishing active inflammatory bowel disease from irritable bowel syndrome.
| Sensitivity % | Specificity % | LR+ | LR− | PPV | NPV | OR | |
|---|---|---|---|---|---|---|---|
| Fecal S100A12 | 86 | 96 | 21.5 | 6.9 | 0.98 | 0.76 | 13.5 |
| Fecal calprotectin | 63 | 86 | 4.5 | 2.3 | 0.90 | 0.51 | 9.9 |
| CRP | 58 | 79 | 2.8 | 1.9 | 0.76 | 0.53 | 3.2 |
| ESR | 56 | 75 | 2.24 | 1.7 | 0.74 | 0.42 | 2.9 |
| CDAI | 27 | 100* | – | – | 1 | 0.24 | – |
| CAI | 63 | 100† | – | – | 1 | 0.38 | – |
CAI, Colitis activity index; CDAI, Crohn's disease activity index; LR−, negative likelihood ratio; LR+, positive likelihood ratio; NPV, negative predictive value; OR, odds ratio; PPV, positive predictive value.
*CDAI < 150 in inactive Crohn's disease (n = 6), †CAI ⩽ 5 in inactive ulcerative colitis (n = 3).