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. 1989 Mar;171(3):1513–1518. doi: 10.1128/jb.171.3.1513-1518.1989

Autocide AMI rescues development in dsg mutants of Myxococcus xanthus.

A Rosenbluh 1, E Rosenberg 1
PMCID: PMC209774  PMID: 2493446

Abstract

Low concentrations of autocide AMI rescued aggregation and sporulation in the dsg mutant class of Myxococcus xanthus but were incapable of rescuing asg, bsg, or csg mutants. AMI-induced spores of dsg mutants were resistant to heat and sonication and germinated when plated on nutrient-rich agar. AMI accelerated aggregation and sporulation and increased the final spore number in submerged cultures of a wild-type strain of M. xanthus. Development of M. xanthus was accompanied by release of a fluorescent material (emission maximum, 438 nm) into the supernatant fluid. The release of this material began early and continued throughout development. All Spo- mutant strains tested released significantly reduced levels of this material. These levels were increased in the presence of AMI in all Spo- mutant classes, most dramatically in the dsg mutants.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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