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. 1989 Sep;171(9):5095–5102. doi: 10.1128/jb.171.9.5095-5102.1989

L-serine degradation in Escherichia coli K-12: cloning and sequencing of the sdaA gene.

H S Su 1, B F Lang 1, E B Newman 1
PMCID: PMC210322  PMID: 2504697

Abstract

A new mutant of Escherichia coli K-12 unable to grow with L-serine, glycine, and L-leucine has been isolated by lambda plac Mu insertion and shown to be deficient in L-serine deaminase activity. The corresponding gene, sdaA, has been cloned from a prototrophic strain, and the clone has been characterized and sequenced. The evidence is consistent with the hypothesis that sdaA is the structural gene for L-serine deaminase. However, other possibilities are also considered. No significant homology with previously reported DNA or protein sequences was detected.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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