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. 1989 Nov;171(11):6353–6356. doi: 10.1128/jb.171.11.6353-6356.1989

Characterization of the inverted duplication in the mitochondrial DNA of Candida albicans.

J A Shaw 1, W B Troutman 1, B A Lasker 1, M M Mason 1, W S Riggsby 1
PMCID: PMC210511  PMID: 2681166

Abstract

The mitochondrial DNA (mtDNA) of Candida albicans contains a large inverted duplication. As is the case with most chloroplast DNAs and one other mtDNA, the nonduplicated regions of the molecule occur in two orientations with respect to each other, indicating that internal recombination occurs. Like some other mtDNAs, the C. albicans mtDNA contains a single SalI restriction site located near one end of the large rRNA gene. In contrast to other cases, however, the inverted duplication does not appear to contain any sequences coding for rRNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beggs J. D. Transformation of yeast by a replicating hybrid plasmid. Nature. 1978 Sep 14;275(5676):104–109. doi: 10.1038/275104a0. [DOI] [PubMed] [Google Scholar]
  2. Clark-Walker G. D., McArthur C. R., Sriprakash K. S. Order and orientation of genic sequences in circular mitochondrial DNA from Saccharomyces exiguus: implications for evolution of yeast mtDNAs. J Mol Evol. 1983;19(5):333–341. doi: 10.1007/BF02101636. [DOI] [PubMed] [Google Scholar]
  3. Clark-Walker G. D., Sriprakash K. S. Sequence rearrangements between mitochondrial DNAs of Torulopsis glabrata and Kloeckera africana identified by hybridization with six polypeptide encoding regions from Saccharomyces cerevisiae mitochondrial DNA. J Mol Biol. 1981 Sep 25;151(3):367–387. doi: 10.1016/0022-2836(81)90002-4. [DOI] [PubMed] [Google Scholar]
  4. Dugaiczyk A., Boyer H. W., Goodman H. M. Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures. J Mol Biol. 1975 Jul 25;96(1):171–184. doi: 10.1016/0022-2836(75)90189-8. [DOI] [PubMed] [Google Scholar]
  5. Garber R. C., Yoder O. C. Isolation of DNA from filamentous fungi and separation into nuclear, mitochondrial, ribosomal, and plasmid components. Anal Biochem. 1983 Dec;135(2):416–422. doi: 10.1016/0003-2697(83)90704-2. [DOI] [PubMed] [Google Scholar]
  6. Hudspeth M. E., Shumard D. S., Bradford C. J., Grossman L. I. Organization of Achlya mtDNA: a population with two orientations and a large inverted repeat containing the rRNA genes. Proc Natl Acad Sci U S A. 1983 Jan;80(1):142–146. doi: 10.1073/pnas.80.1.142. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kolodner R., Tewari K. K. Inverted repeats in chloroplast DNA from higher plants. Proc Natl Acad Sci U S A. 1979 Jan;76(1):41–45. doi: 10.1073/pnas.76.1.41. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Palmer J. D., Thompson W. F. Chloroplast DNA rearrangements are more frequent when a large inverted repeat sequence is lost. Cell. 1982 Jun;29(2):537–550. doi: 10.1016/0092-8674(82)90170-2. [DOI] [PubMed] [Google Scholar]
  9. Shumard D. S., Grossman L. I., Hudspeth M. E. Achlya mitochondrial DNA: gene localization and analysis of inverted repeats. Mol Gen Genet. 1986 Jan;202(1):16–23. doi: 10.1007/BF00330510. [DOI] [PubMed] [Google Scholar]
  10. Smith H. O. Recovery of DNA from gels. Methods Enzymol. 1980;65(1):371–380. doi: 10.1016/s0076-6879(80)65048-4. [DOI] [PubMed] [Google Scholar]
  11. Strauss S. H., Palmer J. D., Howe G. T., Doerksen A. H. Chloroplast genomes of two conifers lack a large inverted repeat and are extensively rearranged. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3898–3902. doi: 10.1073/pnas.85.11.3898. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Torres-Bauzá L. J., Riggsby W. S. Protoplasts from yeast and mycelial forms of Candida albicans. J Gen Microbiol. 1980 Aug;119(2):341–349. doi: 10.1099/00221287-119-2-341. [DOI] [PubMed] [Google Scholar]
  13. Wallace D. C. Structure and evolution of organelle genomes. Microbiol Rev. 1982 Jun;46(2):208–240. doi: 10.1128/mr.46.2.208-240.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Wills J. W., Troutman W. B., Riggsby W. S. Circular mitochondrial genome of Candida albicans contains a large inverted duplication. J Bacteriol. 1985 Oct;164(1):7–13. doi: 10.1128/jb.164.1.7-13.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]

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