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. 1964 Aug 1;22(2):413–431. doi: 10.1083/jcb.22.2.413

STRUCTURE OF THE MACULA UTRICULI WITH SPECIAL REFERENCE TO DIRECTIONAL INTERPLAY OF SENSORY RESPONSES AS REVEALED BY MORPHOLOGICAL POLARIZATION

Åke Flock 1
PMCID: PMC2106456  PMID: 14203389

Abstract

The anatomy of the labyrinth and the structure of the macula utriculi of the teleost fish (burbot) Lota vulgaris was studied by dissection, phase contrast, and electron microscopy. The innervating nerve fibers end at the bottom of the sensory cells where two types of nerve endings are found, granulated and non-granulated. The ultrastructure and organization of the sensory hair bundles are described, and the finding that the receptor cells are morphologically polarized by the presence of an asymmetrically located kinocilium in the sensory hair bundle is discussed in terms of directional sensitivity. The pattern of orientation of the hair cells in the macula utriculi was determined, revealing a complicated morphological polarization of the sensory epithelium. The findings suggest that the interplay of sensory responses is intimately related to the directional sensitivity of the receptor cells as revealed by their morphological polarization. The problem of efferent innervation is discussed, and it is concluded that the positional information signaled by the nerve fibers innervating the vestibular organs comprises an intricate pattern of interacting afferent and efferent impulses

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Selected References

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  1. AFZELIUS B. Electron microscopy of the sperm tail; results obtained with a new fixative. J Biophys Biochem Cytol. 1959 Mar 25;5(2):269–278. doi: 10.1083/jcb.5.2.269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Adrian E. D. Discharges from vestibular receptors in the cat. J Physiol. 1943 Mar 25;101(4):389–407. doi: 10.1113/jphysiol.1943.sp003995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CARLSTROM D., ENGSTROM H., HJORTH S. Electron microscopic and x-ray diffraction studies of statoconia. Laryngoscope. 1953 Nov;63(11):1052–1057. doi: 10.1288/00005537-195311000-00002. [DOI] [PubMed] [Google Scholar]
  4. DAVIS H. Some principles of sensory receptor action. Physiol Rev. 1961 Apr;41:391–416. doi: 10.1152/physrev.1961.41.2.391. [DOI] [PubMed] [Google Scholar]
  5. DIJKGRAAF S. The functioning and significance of the lateral-line organs. Biol Rev Camb Philos Soc. 1963 Feb;38:51–105. doi: 10.1111/j.1469-185x.1963.tb00654.x. [DOI] [PubMed] [Google Scholar]
  6. FLOCK A., WERSALL J. A study of the orientation of the sensory hairs of the receptor cells in the lateral line organ of fish, with special reference to the function of the receptors. J Cell Biol. 1962 Oct;15:19–27. doi: 10.1083/jcb.15.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FLOCK A., WERSALL J. Synaptic structures in the lateral line canal organ of the teleost fish Lota vulgaris. J Cell Biol. 1962 May;13:337–343. doi: 10.1083/jcb.13.2.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FRIEDMANN I. Electron microscope observations on in vitro cultures of the isolated fowl embryo otocyst. J Biophys Biochem Cytol. 1959 Mar 25;5(2):263–268. doi: 10.1083/jcb.5.2.263. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HILDING D., WERSALL J. Cholinesterase and its relation to the nerve endings in the inner ear. Acta Otolaryngol. 1962 Sep;55:205–217. doi: 10.3109/00016486209127354. [DOI] [PubMed] [Google Scholar]
  10. JIELOF R., SPOOR A., DE VRIES H. The microphonic activity of the lateral line. J Physiol. 1952 Feb;116(2):137–157. doi: 10.1113/jphysiol.1952.sp004695. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LOWENSTEIN O., ROBERTS T. D. M. The equilibrium function of the otolith organs of the thornback ray (Raja clavata). J Physiol. 1949 Dec;110(3-4):392–415. doi: 10.1113/jphysiol.1949.sp004448. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. PALADE G. E. A small particulate component of the cytoplasm. J Biophys Biochem Cytol. 1955 Jan;1(1):59–68. doi: 10.1083/jcb.1.1.59. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Ross D. A. Electrical studies on the frog's labyrinth. J Physiol. 1936 Feb 8;86(2):117–146. doi: 10.1113/jphysiol.1936.sp003348. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. SCHMIDT R. S. Frog labyrinthine efferent impulses. Acta Otolaryngol. 1963 Feb;56:51–64. doi: 10.3109/00016486309127679. [DOI] [PubMed] [Google Scholar]
  16. SMITH C. A. Microscopic structure of the utricle. Ann Otol Rhinol Laryngol. 1956 Jun;65(2):450–469. doi: 10.1177/000348945606500213. [DOI] [PubMed] [Google Scholar]
  17. TRINCKER D. [Electrophysiology of the vestibular apparatus and the problem of transformation of the mechanical stimulus into nervous excitation]. Confin Neurol. 1960;20:187–195. [PubMed] [Google Scholar]
  18. WERSAELL J., HILDING D., LUNDQUIST P. G. [Ultrastructure and innervation of the cochlear hair cells]. Arch Ohren Nasen Kehlkopfheilkd. 1961;178:106–126. [PubMed] [Google Scholar]

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