Skip to main content
The Journal of Cell Biology logoLink to The Journal of Cell Biology
. 1962 May 1;13(2):233–237. doi: 10.1083/jcb.13.2.233

A KINETIC STUDY OF THE NEURON-GLIA RELATIONSHIP

Holger Hydén 1, Paul W Lange 1
PMCID: PMC2106823  PMID: 14450328

Abstract

Kinetic studies have been performed on the activity of the succinate oxidizing enzyme complex in living nerve cells and glial cells after increasing duration of stimulation. The nerve cells and glia of the lateral vestibular nucleus were used. The results show a clear difference between the neuron and its surrounding glia. The nerve cell reacted by highly increasing the capacity of the electron transporting system, reflecting an increased consumption of energy as a function of the stimulation. The glia, in contrast, did not change in this respect.

Full Text

The Full Text of this article is available as a PDF (304.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CHANG J. J., HILD W. Contractile responses to electrical stimulation of glial cells from the mammalian central nervous system cultivated in vitro. J Cell Comp Physiol. 1959 Feb;53:139–144. doi: 10.1002/jcp.1030530112. [DOI] [PubMed] [Google Scholar]
  2. HAMBERGER A. Oxidation of tricarboxylic acid cycle intermediates by nerve cell bodies and glial cells. J Neurochem. 1961 Oct;8:31–35. doi: 10.1111/j.1471-4159.1961.tb13523.x. [DOI] [PubMed] [Google Scholar]
  3. HYDEN H., LARSSON S. The application of a scanning and computing cell analyser to neurocytological problems. J Neurochem. 1956 Dec;1(2):134–144. doi: 10.1111/j.1471-4159.1956.tb12064.x. [DOI] [PubMed] [Google Scholar]
  4. LARSSON S. A mechanical micro-scanner. Exp Cell Res. 1957 Jun;12(3):666–669. doi: 10.1016/0014-4827(57)90185-4. [DOI] [PubMed] [Google Scholar]
  5. TASAKI I., CHANG J. J. Electric response of glia cells in cat brain. Science. 1958 Nov 14;128(3333):1209–1210. doi: 10.1126/science.128.3333.1209. [DOI] [PubMed] [Google Scholar]
  6. UNGAR G., ASCHHEIM I., PSYCHOYOS S., ROMANO D. V. Reversible changes of protein configuration in stimulated nerve structures. J Gen Physiol. 1957 Mar 20;40(4):635–652. doi: 10.1085/jgp.40.4.635. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Cell Biology are provided here courtesy of The Rockefeller University Press

RESOURCES