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. 1966 Aug 1;30(2):433–436. doi: 10.1083/jcb.30.2.433

THE ANATOMY OF SECRETION IN THE FOLLICULAR CELL OF THE THYROID GLAND

III. The Acute Effect in Vivo of Thyrotropic Hormone on Amino Acid Uptake and Incorporation into Protein by the Mouse Thyroid Gland

Alan S Bradley 1, Steven L Wissig 1
PMCID: PMC2106997  PMID: 5968979

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Selected References

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  1. CARO L. G., PALADE G. E. PROTEIN SYNTHESIS, STORAGE, AND DISCHARGE IN THE PANCREATIC EXOCRINE CELL. AN AUTORADIOGRAPHIC STUDY. J Cell Biol. 1964 Mar;20:473–495. doi: 10.1083/jcb.20.3.473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. DEBONS A. F., PITTMAN J. A. Stimulation of alpha aminoisobutyric acid-C14 uptake in thyroid slices by thyrotropin. Endocrinology. 1962 Jun;70:937–940. doi: 10.1210/endo-70-6-937. [DOI] [PubMed] [Google Scholar]
  3. FIELD J. B., PASTAN I., HERRING B., JOHNSON P. Studies on the mechanism of action of thyroid stimulating hormone on glucose oxidation. Biochim Biophys Acta. 1961 Jul 8;50:513–520. doi: 10.1016/0006-3002(61)90011-7. [DOI] [PubMed] [Google Scholar]
  4. FIELD J. B., PASTAN I., JOHNSON P., HERRING B. Stimulation in vitro of pathways of glucose oxidation in thyroid by thyroid-stimulating hormone. J Biol Chem. 1960 Jul;235:1863–1866. [PubMed] [Google Scholar]
  5. FLORSHEIM W. H., MOSKOWITZ N., SCHWARTZ J. R., MORTON M. E. A new assay for thyrotropic hormone based upon thyroidal phospholipid turnover in vitro. Endocrinology. 1957 Jun;60(6):683–688. doi: 10.1210/endo-60-6-683. [DOI] [PubMed] [Google Scholar]
  6. FREINKEL N. Further observations concerning the action of pituitary thyrotropin on the intermediate metabolism of sheep thyroid tissue in vitro. Endocrinology. 1960 Jun;66:851–859. doi: 10.1210/endo-66-6-851. [DOI] [PubMed] [Google Scholar]
  7. Greenspan F. S., Hargadine J. R. The intracellular localization of pituitary thyrotropic hormone. J Cell Biol. 1965 Jul;26(1):177–185. doi: 10.1083/jcb.26.1.177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. HALL R. Stimulation of purine synthesis in vitro in the calf thyroid by thyroid-stimulating hormone. J Biol Chem. 1963 Jan;238:306–310. [PubMed] [Google Scholar]
  9. HALMI N. S., GRANNER D. K., DOUGHMAN D. J., PETERS B. H., MULLER G. Biphasic effect of TSH on thyroidal iodide collection in rats. Endocrinology. 1960 Jul;67:70–81. doi: 10.1210/endo-67-1-70. [DOI] [PubMed] [Google Scholar]
  10. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  11. MANCINI R. E., VILAR O., DELLACHA J. M., DAVIDSON O. W., CASTRO A. Histological localization in rat tissues of intravenously injected thyrotrophin labeled with a fluorescent dye. J Histochem Cytochem. 1961 May;9:271–277. doi: 10.1177/9.3.271. [DOI] [PubMed] [Google Scholar]
  12. MORTON M. E., SCHWARTZ J. R. The stimulation in vitro of phospholipid synthesis in thyroid tissue by thyrotrophic hormone. Science. 1953 Jan 30;117(3031):103–104. doi: 10.1126/science.117.3031.103. [DOI] [PubMed] [Google Scholar]
  13. NADLER N. J., SARKAR S. K., LEBLOND C. P. Origin of intracellular colloid droplets in the rat thyroid. Endocrinology. 1962 Jul;71:120–129. doi: 10.1210/endo-71-1-120. [DOI] [PubMed] [Google Scholar]
  14. NOVIKOFF A. B., ESSNER E., QUINTANA N. GOLGI APPARATUS AND LYSOSOMES. Fed Proc. 1964 Sep-Oct;23:1010–1022. [PubMed] [Google Scholar]
  15. RAGHUPATHY E., ABRAHAM S., KERKOF P. R., CHAIKOFF I. L. SOME CHARACTERISTICS OF THE SHEEP THYROID GLAND SYSTEM FOR INCORPORATING AMINO ACIDS INTO PROTEIN. Endocrinology. 1964 Mar;74:468–482. doi: 10.1210/endo-74-3-468. [DOI] [PubMed] [Google Scholar]
  16. ROSENBERG I. N., ATHANS J. C., BEHAR A. Effect of thyrotropin on the release of iodide from the thyroid. Endocrinology. 1960 Feb;66:185–199. doi: 10.1210/endo-66-2-185. [DOI] [PubMed] [Google Scholar]
  17. SHELDON H., MCKENZIE J. M., VANNIMWEGAN D. ELECTRON MICROSCOPIC AUTORADIOGRAPHY: THE LOCALIZATION OF I-125 IN SUPPRESSED AND THYROTROPIN-STIMULATED MOUSE THYROID GLAND. J Cell Biol. 1964 Oct;23:200–205. doi: 10.1083/jcb.23.1.200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. WISSIG S. L. The anatomy of secretion in the follicular cells of the thyroid gland. II. The effect of acute thyrotrophic hormone stimulation on the secretory apparatus. J Cell Biol. 1963 Jan;16:93–117. doi: 10.1083/jcb.16.1.93. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Wetzel B. K., Spicer S. S., Wollman S. H. Changes in fine structure and acid phosphatase localization in rat thyroid cells following thyrotropin administration. J Cell Biol. 1965 Jun;25(3):593–618. doi: 10.1083/jcb.25.3.593. [DOI] [PMC free article] [PubMed] [Google Scholar]

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