Skip to main content
PMC home page
The Journal of Cell Biology logoLink to The Journal of Cell Biology
. 1966 Aug 1;30(2):442–450. doi: 10.1083/jcb.30.2.442

RESPONSE OF HEPATIC MICROBODIES TO A HYPOLIPIDEMIC AGENT, ETHYL CHLOROPHENOXYISOBUTYRATE (CPIB)

Donald J Svoboda 1, Daniel L Azarnoff 1
PMCID: PMC2107000  PMID: 5968981

Full Text

The Full Text of this article is available as a PDF (1.0 MB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AZARNOFF D. L., TUCKER D. R., BARR G. A. STUDIES WITH ETHYL CHLOROPHENOXYISOBUTYRATE (CLOFIBRATE). Metabolism. 1965 Sep;14:959–965. doi: 10.1016/0026-0495(65)90111-3. [DOI] [PubMed] [Google Scholar]
  2. Allen J. M., Beard M. E. Alpha-hydroxy acid oxidase: localization in renal microbodies. Science. 1965 Sep 24;149(3691):1507–1509. doi: 10.1126/science.149.3691.1507. [DOI] [PubMed] [Google Scholar]
  3. BAUDHUIN P., MUELLER M., POOLE B., DEDUVE C. NON-MITOCHONDRIAL OXIDIZING PARTICLES (MICROBODIES) IN RAT LIVER AND KIDNEY AND IN TETRAHYMENA PYRIFORMIS. Biochem Biophys Res Commun. 1965 Jun 18;20:53–59. doi: 10.1016/0006-291x(65)90949-6. [DOI] [PubMed] [Google Scholar]
  4. BEST M. M., DUNCAN C. H. HYPOLIPEMIA AND HEPATOMEGALY FROM ETHYL CHLOROPHENOXYISOBUTYRATE (CPIB) IN THE RAT. J Lab Clin Med. 1964 Oct;64:634–642. [PubMed] [Google Scholar]
  5. Baudhuin P., Beaufay H., De Duve C. Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase. J Cell Biol. 1965 Jul;26(1):219–243. doi: 10.1083/jcb.26.1.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bruni C., Porter K. R. The Fine Structure of the Parenchymal Cell of the Normal Rat Liver: I. General Observations. Am J Pathol. 1965 May;46(5):691–755. [PMC free article] [PubMed] [Google Scholar]
  7. HIGASHI T., PETERS T., Jr STUDIES ON RAT LIVER CATALASE. I. COMBINED IMMUNOCHEMICAL AND ENZYMATIC DETERMINATION OF CATALASE IN LIVER CELL FRACTIONS. J Biol Chem. 1963 Dec;238:3945–3951. [PubMed] [Google Scholar]
  8. HIGASHI T., PETERS T., Jr STUDIES ON RAT LIVER CATALASE. II. INCORPORATION OF 14-C-LEUCINE INTO CATALASE OF LIVER CELL FRACTIONS IN VIVO. J Biol Chem. 1963 Dec;238:3952–3954. [PubMed] [Google Scholar]
  9. HRUBAN Z., SWIFT H. URICASE: LOCALIZATION IN HEPATIC MICROBODIES. Science. 1964 Dec 4;146(3649):1316–1318. doi: 10.1126/science.146.3649.1316. [DOI] [PubMed] [Google Scholar]
  10. HRUBAN Z., SWIFT H., WISSLER R. W. Alterations in the fine structure of hepatocytes produced by beta-3-thienylalanine. J Ultrastruct Res. 1963 Apr;8:236–250. doi: 10.1016/s0022-5320(63)90005-4. [DOI] [PubMed] [Google Scholar]
  11. Hess R., Stäubli W., Riess W. Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat. Nature. 1965 Nov 27;208(5013):856–858. doi: 10.1038/208856a0. [DOI] [PubMed] [Google Scholar]
  12. Hruban Z., Swift H., Rechcigl M., Jr Fine structure of transplantable hepatomas of the rat. J Natl Cancer Inst. 1965 Sep;35(3):459–495. doi: 10.1093/jnci/35.3.459. [DOI] [PubMed] [Google Scholar]
  13. JONES D., GRESHAM G. A., HOWARD A. N. THE EFFECT OF ATROMID ON ARTERIAL DISEASE INDUCED BY SEMI-SYNTHETIC DIET IN THE RABBIT. J Atheroscler Res. 1963 Sep-Dec;3:716–724. doi: 10.1016/s0368-1319(63)80057-5. [DOI] [PubMed] [Google Scholar]
  14. KARNOVSKY M. J. Simple methods for "staining with lead" at high pH in electron microscopy. J Biophys Biochem Cytol. 1961 Dec;11:729–732. doi: 10.1083/jcb.11.3.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PAGET G. E. EXPERIMENTAL STUDIES OF THE TOXICITY OF ATROMID WITH PARTICULAR REFERENCE TO FINE STRUCTURAL CHANGES IN THE LIVERS OF RODENTS. J Atheroscler Res. 1963 Sep-Dec;3:729–736. doi: 10.1016/s0368-1319(63)80059-9. [DOI] [PubMed] [Google Scholar]
  16. SVOBODA D., HIGGINSON J. ULTRASTRUCTURAL CHANGES PRODUCED BY PROTEIN AND RELATED DEFICIENCIES IN THE RAT LIVER. Am J Pathol. 1964 Sep;45:353–379. [PMC free article] [PubMed] [Google Scholar]
  17. THORP J. M., WARING W. S. Modification of metabolism and distribution of lipids by ethyl chlorophenoxyisobutyrate. Nature. 1962 Jun 9;194:948–949. doi: 10.1038/194948a0. [DOI] [PubMed] [Google Scholar]
  18. Tsukada H., Mochizuki Y., Fujiwara S. The nucleoids of rat liver cell microbodies. Fine structure and enzymes. J Cell Biol. 1966 Mar;28(3):449–460. doi: 10.1083/jcb.28.3.449. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Cell Biology are provided here courtesy of The Rockefeller University Press

RESOURCES