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. 1988 Feb;170(2):744–750. doi: 10.1128/jb.170.2.744-750.1988

Developmental regulation of tandem promoters for the major outer membrane protein gene of Chlamydia trachomatis.

R S Stephens 1, E A Wagar 1, U Edman 1
PMCID: PMC210717  PMID: 2448291

Abstract

Chlamydia trachomatis has a biphasic developmental cycle which is characterized by qualitative and quantitative changes in protein expression. The molecular mechanisms that mediate these changes are unknown. Evidence for transcriptional regulation of the chlamydial major outer membrane protein gene (omp1) was found by Northern hybridization of RNA isolated sequentially during the chlamydial developmental cycle. Early in the growth cycle a single transcript was detected, which was followed hours later in the cycle by an additional transcript. Mapping of the initiating nucleotide for each transcript suggested that this gene is regulated by differential transcription from tandem promoters.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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