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. 1967 Jul 1;34(1):15–33. doi: 10.1083/jcb.34.1.15

OBLIQUELY STRIATED MUSCLE

III. Contraction Mechanism of Ascaris Body Muscle

Jack Rosenbluth 1
PMCID: PMC2107232  PMID: 6040534

Abstract

Segments of the obliquely striated body muscle of Ascaris were fixed at minimum body length after treatment with acetylcholine and at maximum body length after treatment with piperazine citrate and then studied by light and electron microscopy. Evidence was found for two mechanisms of length change: sliding of thin filaments with respect to thick filaments such as occurs in cross-striated muscle, and shearing of thick filaments with respect to each other such that the degree of their stagger increases with extension and decreases with shortening. The shearing mechanism could account for great extensibility in this muscle and in nonstriated muscles in general and could underlie other manifestations of "plasticity" as well. In addition, it is suggested that the contractile apparatus is attached to the endomysium in such a way that the sarcomeres can act either in series, as in cross-striated muscle, or individually. Since the sarcomeres are virtually longitudinal in orientation and are almost coextensive with the muscle fiber, it would, therefore, be possible for a single sarcomere contracting independently to develop tension effectively between widely separated points on the fiber surface, thus permitting very efficient maintenance of isometric tension.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bárány M., Bárány K., Gaetjens E., Bailin G. Chicken gizzard myosin. Arch Biochem Biophys. 1966 Jan;113(1):205–222. doi: 10.1016/0003-9861(66)90175-5. [DOI] [PubMed] [Google Scholar]
  2. DEBELL J. T., DELCASTILLO J., SANCHEZ V. ELECTROPHYSIOLOGY OF THE SOMATIC MUSCLE CELLS OF ASCARIS LUMBRICOIDES. J Cell Physiol. 1963 Oct;62:159–177. doi: 10.1159/000007808. [DOI] [PubMed] [Google Scholar]
  3. Elliott G. F., Lowy J., Millman B. M. X-ray diffraction from living striated muscle during contraction. Nature. 1965 Jun 26;206(991):1357–1358. doi: 10.1038/2061357a0. [DOI] [PubMed] [Google Scholar]
  4. FRANZINI-ARMSTRONG C., PORTER K. R. SARCOLEMMAL INVAGINATIONS CONSTITUTING THE T SYSTEM IN FISH MUSCLE FIBERS. J Cell Biol. 1964 Sep;22:675–696. doi: 10.1083/jcb.22.3.675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. HUXLEY A. F. A DISCUSSION ON THE PHYSICAL AND CHEMICAL BASIS OF MUSCULAR CONTRACTION. INTRODUCTORY REMARKS. Proc R Soc Lond B Biol Sci. 1964 Oct 27;160:434–437. doi: 10.1098/rspb.1964.0052. [DOI] [PubMed] [Google Scholar]
  6. HUXLEY H. E. STRUCTURAL ARRANGEMENTS AND THE CONTRACTION MECHANISM IN STRIATED MUSCLE. Proc R Soc Lond B Biol Sci. 1964 Oct 27;160:442–448. doi: 10.1098/rspb.1964.0054. [DOI] [PubMed] [Google Scholar]
  7. JOHNSON W. H. Tonic mechanisms in smooth muscles. Physiol Rev Suppl. 1962 Jul;5:113–159. [PubMed] [Google Scholar]
  8. KARNOVSKY M. J. Simple methods for "staining with lead" at high pH in electron microscopy. J Biophys Biochem Cytol. 1961 Dec;11:729–732. doi: 10.1083/jcb.11.3.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Page S. G. A comparison of the fine structures of frog slow and twitch muscle fibers. J Cell Biol. 1965 Aug;26(2):477–497. doi: 10.1083/jcb.26.2.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. RICHARDSON K. C., JARETT L., FINKE E. H. Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 1960 Nov;35:313–323. doi: 10.3109/10520296009114754. [DOI] [PubMed] [Google Scholar]
  12. ROSENBLUTH J. SMOOTH MUSCLE: AN ULTRASTRUCTURAL BASIS FOR THE DYNAMIC OF ITS CONTRACTION. Science. 1965 Jun 4;148(3675):1337–1339. doi: 10.1126/science.148.3675.1337. [DOI] [PubMed] [Google Scholar]
  13. Rosenbluth J. Ultrastructural organization of obliquely striated muscle fibers in Ascaris lumbricoides. J Cell Biol. 1965 Jun;25(3):495–515. doi: 10.1083/jcb.25.3.495. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Rosenbluth J. Ultrastructure of somatic muscle cells in Ascaris lumbricoides. II. Intermuscular junctions, neuromuscular junctions, and glycogen stores. J Cell Biol. 1965 Aug;26(2):579–591. doi: 10.1083/jcb.26.2.579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. WATSON M. L. Staining of tissue sections for electron microscopy with heavy metals. J Biophys Biochem Cytol. 1958 Jul 25;4(4):475–478. doi: 10.1083/jcb.4.4.475. [DOI] [PMC free article] [PubMed] [Google Scholar]

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