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. 1969 Jul 1;42(1):235–240. doi: 10.1083/jcb.42.1.235

INORGANIC PYROPHOSPHATASE OF RAT LIVER MITOCHONDRIA

Correlation of Latency with Catalytic Properties and Intramitochondrial Location

Lloyd Schick 1, Larry G Butler 1
PMCID: PMC2107579  PMID: 4306787

Abstract

Stimulation of Mg2+-dependent inorganic pyrophosphatase activity several fold by disruption of mitochondrial membranes does not appreciably alter the catalytic properties of the enzyme. Stimulation is due to increased accessibility of substrate to the enzyme, which is not solublized on activation. The enzyme is attached to the inside of the inner membrane, and under physiological conditions probably hydrolyzes only intramitochondrially-produced PPi.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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