Abstract
Cytochalasin B produces multinucleated erythroid cells in tissue cultures of very young chick blastoderms. There is no apparent qualitative interference with differentiation and maturation of erythroid cells, but the amounts produced are reduced 4- and 10-fold. These effects of cytochalasin are readily reversible.
Full Text
The Full Text of this article is available as a PDF (453.7 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Carter S. B. Effects of cytochalasins on mammalian cells. Nature. 1967 Jan 21;213(5073):261–264. doi: 10.1038/213261a0. [DOI] [PubMed] [Google Scholar]
- Hagopian H. K., Ingram V. M. Developmental changes of erythropoiesis in cultured chick blastoderms. J Cell Biol. 1971 Nov;51(21):440–451. doi: 10.1083/jcb.51.2.440. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moss B., Ingram V. M. Hemoglobin synthesis during amphibian metamorphosis. I. Chemical studies on the hemoglobins from the larval and adult stages of Rana catesbeiana. J Mol Biol. 1968 Mar 28;32(3):481–492. doi: 10.1016/0022-2836(68)90336-7. [DOI] [PubMed] [Google Scholar]
- Wessells N. K., Spooner B. S., Ash J. F., Bradley M. O., Luduena M. A., Taylor E. L., Wrenn J. T., Yamada K. Microfilaments in cellular and developmental processes. Science. 1971 Jan 15;171(3967):135–143. doi: 10.1126/science.171.3967.135. [DOI] [PubMed] [Google Scholar]