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. 1970 Dec 1;47(3):568–576. doi: 10.1083/jcb.47.3.568

THE EFFECTS OF HIGH HYDROSTATIC PRESSURE ON THE MICROTUBULES OF TETRAHYMENA PYRIFORMIS

John R Kennedy 1, Arthur M Zimmerman 1
PMCID: PMC2108149  PMID: 5497538

Abstract

Exposure of Tetrahymena pyriformis to 7,500 or 10,000 psi of hydrostatic pressure for 2, 5, or 10 min intervals results in a change in cell shape and ciliary activity. Shape changes occur concurrently with a degradation of longitudinal microtubules in a posterior to anterior direction. High pressure also causes a disruption of ciliary activity. Fine structural analysis reveals a breakdown (presumably microtubule depolymerization) of the central ciliary microtubules. The depolymerization begins at the junction of the central ciliary microtubules with the axosome and progresses distally along the ciliary shaft for a distance of about 0.5 µ.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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