Abstract
Electron probe microanalysis has revealed that vesicular or cisternal structures containing electron-dense material in frog ependymal glial cells contain deposits of calcium and phosphorus. The so-called "osmiophilic particles" in human astrocytes also contain calcium. It is suggested that these organelles are storage sites of calcium.
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Selected References
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- Andrews J. M., Andrews R. L. The significance of dense core particles in subacute demyelinating disease in an adult. Lab Invest. 1973 Feb;28(2):236–243. [PubMed] [Google Scholar]
- Brightman M. W., Reese T. S. Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol. 1969 Mar;40(3):648–677. doi: 10.1083/jcb.40.3.648. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gambetti P., DiMauro S., Baker L. Nervous system in Pompe's disease. Ultrastructure and biochemistry. J Neuropathol Exp Neurol. 1971 Jul;30(3):412–430. doi: 10.1097/00005072-197107000-00008. [DOI] [PubMed] [Google Scholar]
- Gonatas N. K., Martin J., Evangelista I. The osmiophilic particles of astrocytes. Viruses, lipid droplets or products of secretion? J Neuropathol Exp Neurol. 1967 Jul;26(3):369–376. doi: 10.1097/00005072-196707000-00002. [DOI] [PubMed] [Google Scholar]
- Gonatas N. K., Shy G. M. Virus-like particles in sub-acute sclerosing encephalitis. Nature. 1965 Dec 25;208(5017):1338–1339. doi: 10.1038/2081338b0. [DOI] [PubMed] [Google Scholar]
- HUXLEY H. E., ZUBAY G. Preferential staining of nucleic acid-containing structures for electron microscopy. J Biophys Biochem Cytol. 1961 Nov;11:273–296. doi: 10.1083/jcb.11.2.273. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kruger L., Maxwell D. S. The fine structure of ependymal processes in the teleost optic tectum. Am J Anat. 1966 Nov;119(3):479–497. doi: 10.1002/aja.1001190308. [DOI] [PubMed] [Google Scholar]
- Oschman J. L., Wall B. J. Calcium binding to intestinal membranes. J Cell Biol. 1972 Oct;55(1):58–73. doi: 10.1083/jcb.55.1.58. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PEACHEY L. D. Thin sections. I. A study of section thickness and physical distortion produced during microtomy. J Biophys Biochem Cytol. 1958 May 25;4(3):233–242. doi: 10.1083/jcb.4.3.233. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Potter H. D. The distribution of neurofibrils coextensive with microtubules and neurofilaments in dendrites and axons of the tectum, cerebellum and pallium of the frog. J Comp Neurol. 1971 Dec;143(4):385–409. doi: 10.1002/cne.901430402. [DOI] [PubMed] [Google Scholar]
- REYNOLDS E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J Cell Biol. 1963 Apr;17:208–212. doi: 10.1083/jcb.17.1.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Somlyo A. P., Somlyo A. V., Devine C. E., Peters P. D., Hall T. A. Electron microscopy and electron probe analysis of mitochondrial cation accumulation in smooth muscle. J Cell Biol. 1974 Jun;61(3):723–742. doi: 10.1083/jcb.61.3.723. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zadunaisky J. A., Wald F., De Robertis E. D. Osmotic behavior and glial changes in isolated frog brains. Prog Brain Res. 1965;15:196–218. doi: 10.1016/s0079-6123(08)60947-4. [DOI] [PubMed] [Google Scholar]