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. 1975 Aug 1;66(2):445–451. doi: 10.1083/jcb.66.2.445

Actin-like filaments in bone cells of cultured mouse calvaria as demonstrated by binding to heavy meromyosin

PMCID: PMC2109565  PMID: 1095601

Abstract

A variety of intracellular filaments (50-70 A in diameter) found in bone cells was shown to bind specifically to HMM. Because of this property, these filaments are probably biochemically similar to muscle actin. in osteoblasts and osteocytes, these reactive filaments were oriented in bundles parallel to the plasma membrane and filling the cell processes. In the osteoclast the filaments along the cell membrane were not so highly organized. In the clear zone, the quiescent part of the cell adjacent to the motile ruffled border, organized filament bundles were oriented perpendicular to the cell membrane and terminated in short processes at the bone surface. These filaments were also reactive with HMM. The possible significance of the filaments with respect to the physiology of bone cells is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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