Abstract
The structure of regions with a high concentration of ACh receptors (clusters) on cultured skeletal muscle myotubes was examined by immunoperoxidase staining of bound alphaBT. The clusters did not appear to differ from the other regions except in their higher concentration of receptor.
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Selected References
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- Daniels M. P., Vogel Z. Immunoperoxidase staining of alpha-bungarotoxin binding sites in muscle endplates shows distribution of acetylcholine receptors. Nature. 1975 Mar 27;254(5498):339–341. doi: 10.1038/254339a0. [DOI] [PubMed] [Google Scholar]
- Fertuck H. C., Salpeter M. M. Localization of acetylcholine receptor by 125I-labeled alpha-bungarotoxin binding at mouse motor endplates. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1376–1378. doi: 10.1073/pnas.71.4.1376. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fischbach G. D., Cohen S. A. The distribution of acetylcholine sensitivity over uninnervated and innervated muscle fibers grown in cell culture. Dev Biol. 1973 Mar;31(1):147–162. doi: 10.1016/0012-1606(73)90326-6. [DOI] [PubMed] [Google Scholar]
- Hourani B. T., Torain B. F., Henkart M. P., Carter R. L., Marchesi V. T., Fischbach G. D. Acetylcholine receptors of cultured muscle cells demonstrated with ferritin-alpha-bungarotoxin conjugates. J Cell Sci. 1974 Nov;16(2):473–479. doi: 10.1242/jcs.16.2.473. [DOI] [PubMed] [Google Scholar]
- Kuffler S. W., Dennis M. J., Harris A. J. The development of chemosensitivity in extrasynaptic areas of the neuronal surface after denervation of parasympathetic ganglion cells in the heart of the frog. Proc R Soc Lond B Biol Sci. 1971 Apr 27;177(1049):555–563. doi: 10.1098/rspb.1971.0047. [DOI] [PubMed] [Google Scholar]
- Lillie R. D., Pizzolato P. Histochemical use of borohydrides as aldehyde blocking reagents. Stain Technol. 1972 Jan;47(1):13–16. doi: 10.3109/10520297209116528. [DOI] [PubMed] [Google Scholar]
- MILEDI R. Junctional and extra-junctional acetylcholine receptors in skeletal muscle fibres. J Physiol. 1960 Apr;151:24–30. [PMC free article] [PubMed] [Google Scholar]
- Sytkowski A. J., Vogel Z., Nirenberg M. W. Development of acetylcholine receptor clusters on cultured muscle cells. Proc Natl Acad Sci U S A. 1973 Jan;70(1):270–274. doi: 10.1073/pnas.70.1.270. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vogel Z., Sytkowski A. J., Nirenberg M. W. Acetylcholine receptors of muscle grown in vitro. Proc Natl Acad Sci U S A. 1972 Nov;69(11):3180–3184. doi: 10.1073/pnas.69.11.3180. [DOI] [PMC free article] [PubMed] [Google Scholar]
- White N. K., Hauschka S. D. Muscle development in vitro. A new conditioned medium effect on colony differentiation. Exp Cell Res. 1971 Aug;67(2):479–482. doi: 10.1016/0014-4827(71)90437-x. [DOI] [PubMed] [Google Scholar]