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. 1988 Jul;170(7):3237–3242. doi: 10.1128/jb.170.7.3237-3242.1988

Colicin E8, a DNase which indicates an evolutionary relationship between colicins E2 and E3.

M Toba 1, H Masaki 1, T Ohta 1
PMCID: PMC211275  PMID: 3290201

Abstract

Colicin E8-J and its immunity protein were characterized with regard to their activities and gene structures. Colicin E8 is a complex of proteins A and B; protein A (the naked E8) exhibits an apparently nonspecific DNase activity that is inhibited by protein B (the immunity protein), as in the case of colicin E2. The nucleotide sequence of the downstream half of the colicin operon of ColE8-J was determined to be highly homologous to that of ColE2-P9, with the exception of the hot spot region of the 3'-terminal segment of the colicin gene and the adjacent immunity gene. The immE2-like gene of ColE3-CA38 was, as assumed previously, extensively homologous to the immE8 gene of ColE8-J, and thus, ColE8-J was shown to be situated between ColE2-P9 and ColE3-CA38 in the evolution of the E-group Col plasmids.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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