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. 1982 Dec 1;95(3):933–942. doi: 10.1083/jcb.95.3.933

Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation

PMCID: PMC2112917  PMID: 7153252

Abstract

Neutrophils isolated from the blood were compared to those from inflammatory exudates in the peritoneal cavity of guinea pigs. Inflammatory neutrophils were shown to have 10-fold more glycogen than blood neutrophils. This was also reflected in the morphology of these cells. The large accumulations of glycogen in inflammatory neutrophils exists in ordered arrays of beta-granules. Other morphological changes including accumulations of lipid droplets and a decrease in the number of lysosomal granules also accompany the change from blood neutrophils to inflammatory neutrophils. These results show that there are major metabolic differences in the two types of neutrophils.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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