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. 1988 Aug;170(8):3427–3434. doi: 10.1128/jb.170.8.3427-3434.1988

Replication termination for staphylococcal plasmids: plasmids pT181 and pC221 cross-react in the termination process.

S Iordanescu 1, S J Projan 1
PMCID: PMC211311  PMID: 3403507

Abstract

We present data which indicate that (i) the origin of replication of plasmids pT181 and pC221 can also function as termination signals; (ii) termination of replication occurs when a round of replication initiated either by RepC at the pT181 origin or by RepD at the pC221 origin reaches either of these origins, proving that the two plasmids cross-react for termination of replication; and (iii) the replication initiated at the origin of another staphylococcal plasmid, pE194, does not terminate at the origin of pT181 or pC221, indicating the existence of a specific relationship between the initiation and termination of a replication event.

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Selected References

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