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. 1988 Oct;170(10):4991–4994. doi: 10.1128/jb.170.10.4991-4994.1988

Bleomycin-induced DNA repair by Saccharomyces cerevisiae ATP-dependent polydeoxyribonucleotide ligase.

C W Moore 1
PMCID: PMC211556  PMID: 2459112

Abstract

In contrast to ligase-deficient (cdc9) Saccharomyces cerevisiae, which did not rejoin bleomycin-induced DNA breaks, ligase-proficient (CDC9) yeast cells eliminated approximately 90% of DNA breaks within 90 to 120 min after treatment. Experimental conditions restricted enzymatic removal of the unusual 3'-phosphoglycolate termini in DNA cleaved by bleomycin and involved doses producing equivalent numbers of DNA breaks or doses producing equivalent killing.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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