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. 1988 Nov;170(11):5371–5374. doi: 10.1128/jb.170.11.5371-5374.1988

An in vivo complex with DNA photolyase blocks UV mutagenesis targeted at a thymine-cytosine dimer in Escherichia coli.

M Ruiz-Rubio 1, K Yamamoto 1, R Bockrath 1
PMCID: PMC211616  PMID: 3053661

Abstract

UV mutation frequency responses for two types of Escherichia coli prototrophic mutant were measured. Only the response associated with a mutation targeted by a thymine-cytosine pyrimidine dimer was reduced in the dark in cells with amplified DNA photolyase. This specific reduction is attributed to the interruption of mutational DNA synthesis by a photolyase complex at the targeting dimer.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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