Table 4 Overlapping regions of linkage for pulmonary function phenotypes.
| Chromosome | Present study | Previous studies | |||
|---|---|---|---|---|---|
| Phenotype | LOD score (cM) | Author, year | Phenotype/Population | LOD score (cM) | |
| 2 | FEV1/FVC, pre‐BD | 1.53 (245) | Palmer, 20037 | FEV1/FVC, post‐BD/Early‐onset COPD | 4.42 (222) |
| Malhotra, 200331 | FEV1/FVC, pre‐BD/General population | 2.36 (216–251)* | |||
| Postma, 20053 | FEV1/FVC, pre‐BD/Asthma | 4.92 (195) | |||
| 4 | FEV1/FVC, pre‐BD | 1.50 (95) | Wilk, 200330 | FEV1/FVC, pre‐BD/General population | 1.64 (89.3) |
| Ferreira, 20052 | FEV1/FVC, pre‐BD/Asthma | 2.07† (94) | |||
| 7 | FEV1, pre‐BD | 1.53 (11) | Bouzigon, 200433 | FEV1 % predicted, pre‐BD/Asthma | 2.17 (17.7) |
Chromosomal regions with LOD score ⩾1.5 in the present study (all subjects) and in at least one previous study are shown.
*1−LOD drop support interval.
†−log10 (p Value).