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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1898 Nov 1;3(6):573–583. doi: 10.1084/jem.3.6.573

THE FATE OF THE GIANT CELLS WHICH FORM IN THE ABSORPTION OF COAGULATED BLOOD SERUM IN THE ANTERIOR CHAMBER OF THE RABBIT'S EYE

Ludvig Hektoen
PMCID: PMC2117985  PMID: 19866880

Abstract

The conclusion seems warranted that the giant cells formed in the absorption of coagulated blood serum inserted into the anterior chamber of the rabbit's eye subdivide again into uninuclear small cells that take part with other new-formed cells derived from the lining of this space to form a densely fibrillated mass of tissue that resembles quite closely the cornea in its structure. This demonstration materially strengthens the opinion expressed by the writer in his previous article in this Journal,* that the giant cells in healing non-degenerated tuberculous tissue may separate into small living cells, and that the giant cells of tuberculosis are not necrobiotic elements from the very moment and from the very mode of their formation, as has been the general teaching, especially in Germany.

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