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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1901 Oct 1;5(6):635–642. doi: 10.1084/jem.5.6.635

NOTES UPON THE AGGLUTINATIONS OBTAINED BY INTRAPERITONEAL INSERTION OF CELLOIDIN CAPSULES CONTAINING BACILLI AND UPON A MODE OF PREPARING SUCH CAPSULES

John McCrae 1
PMCID: PMC2118029  PMID: 19866960

Abstract

1. Capsules made as described above allow dialysis, when placed in the peritoneal cavity. 2. The normal tissues, unstimulated, do not possess the power of causing agglutination; they do not require to be stimulated by the presence of the bacterial bodies, but will produce their share of the agglutinins when acted upon by the bacillary products. 3. Agglutination follows the insertion, in the peritoneal cavity, of "capsuled" bacilli; it gradually increases in degree, and on the removal of the capsule containing the bacilli, begins to disappear. 4. Varieties of bacilli, related closely in morphology and cultural reactions, do not, as a rule, produce serums which inter-agglutinate.

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