Vol. 203, No. 1, January 23, 2006. Pages 99-100.
All data in the bottom row of Table II should have been shifted one column to the right. The corrected table appears below.
Table II.
Mutations in VH3-23-Cγ transcripts from PBL from ATRD patients and controlsa
| Clones
|
Mutations in V region
|
Clustering ratio
|
R/S
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Age (yr) | All | Distinct | Unmutated | Total | % bp | CDR/FRb | CDRs | FRs | |
| ATRD patients | |||||||||
| ATRD1 | 25 | 15 | 13 | 0 | 302 | 8.6 | 0.73 | 3.4 | 1.8 |
| ATRD2 | 13 | 15 | 14 | 2 | 258 | 6.8 | 0.73 | 3.7 | 1.7 |
| ATRD3 | 15 | 6 | 6 | 0 | 194 | 11.9 | 0.62 | 3.9 | 2.0 |
| Total | 36 | 33 | 2 | 754 | 8.4 | 0.70 | 3.6 | 1.8 | |
| Controls | |||||||||
| C1 | 14 | 12 | 11 | 1 | 100 | 3.4 | 1.22 | 5.9 | 1.5 |
| C2 | adult | 11 | 11 | 0 | 275 | 9.3 | 0.73 | 4.5 | 1.7 |
| C3 | 28 | 6 | 6 | 0 | 147 | 9.0 | 0.69 | 5.7 | 2.0 |
| C4 | 24 | 8 | 8 | 0 | 178 | 8.2 | 0.51 | 14.0 | 2.2 |
| C5 | 30 | 4 | 4 | 0 | 49 | 4.5 | 0.53 | c | 1.1 |
| Total | 41 | 40 | 1 | 749 | 6.9 | 0.70 | 6.2 | 1.8 | |
Total RNA was prepared from PBL from all the patients and controls, except for donor C2; buffycoat was obtained and CD27 positive B cells were used.
FR, framework region.
Too few mutations to give a reliable ratio.
