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. 1987 May;169(5):2284–2286. doi: 10.1128/jb.169.5.2284-2286.1987

Peroxisomal localization and activation by bivalent metal ions of ureidoglycolate lyase, the enzyme involved in urate degradation in Candida tropicalis.

Y Takada, N Tsukiji
PMCID: PMC212155  PMID: 3571167

Abstract

Ureiodoglycolate lyase (EC 4.3.2.3) was found only in the peroxisomes in urate-induced Candida tropicalis. The enzyme was markedly activated by the bivalent metal ions Mn2+, Fe2+, and Ni2+. The activation by Mn2+ was suggested to be the result of its binding to the apoenzyme.

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Selected References

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