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. 1987 May;169(5):2322–2325. doi: 10.1128/jb.169.5.2322-2325.1987

Some properties of subunits of DNA gyrase from Pseudomonas aeruginosa PAO1 and its nalidixic acid-resistant mutant.

Y Inoue, K Sato, T Fujii, K Hirai, M Inoue, S Iyobe, S Mitsuhashi
PMCID: PMC212172  PMID: 3032915

Abstract

Subunits A and B of DNA gyrase were purified from Pseudomonas aeruginosa PAO1 and its mutant, which was resistant to nalidixic acid. Inhibition tests of DNA gyrases reconstituted with a combination of subunits from the two strains showed that an alteration of subunit A but not subunit B caused bacteria to resist fluoroquinolones.

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Selected References

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