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. 1987 Jun;169(6):2896–2898. doi: 10.1128/jb.169.6.2896-2898.1987

Acylation of glycerol 3-phosphate is the sole pathway of de novo phospholipid synthesis in Escherichia coli.

T K Ray, J E Cronan Jr
PMCID: PMC212209  PMID: 3294813

Abstract

The inhibition of phospholipid synthesis engendered by starving glycerol 3-phosphate (G3P) auxotrophs of Escherichia coli (plsB or gpsA) for G3P is incomplete; 5 to 10% of the normal rate of phospholipid synthesis remains, even after prolonged starvation. We report that G3P starvation of a strain having lesions in both the gpsA and plsB genes resulted in essentially complete (greater than 98.5%) inhibition of phospholipid synthesis, indicating that all de novo glycerolipid synthesis in E. coli proceeds by acylation of G3P.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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