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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1908 Sep 5;10(5):690–733. doi: 10.1084/jem.10.5.690

AN ANALYSIS OF FOUR HUNDRED CASES OF EPIDEMIC MENINGITIS TREATED WITH THE ANTI-MENINGITIS SERUM

Simon Flexner 1, James W Jobling 1
PMCID: PMC2124538  PMID: 19867159

Abstract

It is our belief that the analyses of histories of cases of epidemic meningitis which have been presented in this article furnish convincing proof that the antimeningitis serum when used by the subdural method of injection, in suitable doses and at proper intervals, is capable of reducing the period of illness; of preventing, in large measure, the chronic lesions and types of the infection; of bringing about complete restoration to health, in all but a very small number of the recovered, thus lessening the serious, deforming, and permanent consequences of meningitis; and of greatly diminishing the fatalities due to the disease.

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