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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1907 Sep 21;9(5):569–577. doi: 10.1084/jem.9.5.569

EXPERIMENTAL LIVER NECROSIS; IV. NUCLEIN METABOLISMS

Holmes C Jackson 1, Richard M Pearce 1
PMCID: PMC2124686  PMID: 19867111

Abstract

In necrosis of the liver of the dog produced by haemotoxic immune sera, the increased excretion of uric acid, purin bases and inorganic phosphorus pentoxide is the result of the hydrolysis of nuclear material occurring during the autolysis of the necrotic tissue.

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