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. 1910 Jul 23;12(4):551–555. doi: 10.1084/jem.12.4.551

A STUDY OF AN EXTREMELY PURE PREPARATION OF RICIN

Cyrus W Field 1
PMCID: PMC2124802  PMID: 19867341

Abstract

1. By following the method of Osborne, Mendel and Harris, we can obtain an extremely potent toxin from the castor bean. 2. It would appear, as a result of testing this preparation at the end of two and a half years, that the agglutinating function and the toxic function are two distinct properties. 3. This result is also borne out by the behavior under the electric current; either we are dealing with two different substances or else with a single substance with two distinct toxiphore groups, one of which is stable and the other labile.

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Selected References

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  1. Flexner S. THE HISTOLOGICAL CHANGES PRODUCED BY RICIN AND ABRIN INTOXICATIONS. J Exp Med. 1897 Mar 1;2(2):197–216. doi: 10.1084/jem.2.2.197. [DOI] [PMC free article] [PubMed] [Google Scholar]

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