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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1912 Apr 1;15(4):397–403. doi: 10.1084/jem.15.4.397

THE INFLUENCE OF HEAT ON DIFFERENT SERA AS CULTURE MEDIA FOR GROWING TISSUES

Ragnvald Ingebrigtsen 1
PMCID: PMC2124928  PMID: 19867533

Abstract

1. Bone marrow of guinea pigs grows better in autogenic than in homogenic serum. 2. Bone marrow of guinea pigs grows more extensively and rapidly in unheated than in heated autogenic and homogenic serum (56° C. for half an hour). 3. In different heterogenic sera, there are differences in the growth of the tissue. In none of the sera examined, was the growth so extensive as in homogenic and autogenic serum. 4. Heated heterogenic serum is a better culture medium and shows more extensive tissue growth than normal unheated heterogenic serum.

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