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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1914 Jan 1;19(1):70–88. doi: 10.1084/jem.19.1.70

FURTHER OBSERVATIONS AND EXPERIMENTS ON GOITRE (SO CALLED THYROID CARCINOMA) IN BROOK TROUT (SALVELINUS FONTINALIS)

III. ITS PREVENTION AND CURE.

David Marine 1
PMCID: PMC2125139  PMID: 19867750

Abstract

1. Goitre in fish is a non-infectious, non-contagious, symptomatic manifestation of a fault of nutrition, the exact biochemical nature of which has not been determined. 2. Feeding the highly artificial and incomplete diet of liver is the major etiological factor in bringing about this fault of nutrition which is at once corrected by feeding whole sea fish. 3. Water plays no essential part in the etiology, transmission, or distribution of the disease in the fish of this hatchery.

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