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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1914 Apr 1;19(4):362–371. doi: 10.1084/jem.19.4.362

OBSERVATIONS ON A STRAIN OF SPIROCHÆTA PALLIDA ISOLATED FROM THE NERVOUS SYSTEM

Henry J Nichols 1
PMCID: PMC2125174  PMID: 19867775

Abstract

A strain of Spirochœta pallida isolated from the nervous system has shown the following constant characters: (1) thick form; (2) the production of hard, well demarcated lesions with necrotic centers; (3) a characteristic location of the lesion; (4) a short incubation period; (5) a tendency to generalize with lesions of the skin and eye, following local inoculation of the testicle and scrotum. It is suggested that these characters constitute a definite strain of highly invasive power and that a classification of members of the pallida group may be made in accordance with this power.

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Selected References

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  1. Noguchi H. MORPHOLOGICAL AND PATHOGENIC VARIATIONS IN TREPONEMA PALLIDUM. J Exp Med. 1912 Feb 1;15(2):201–204. doi: 10.1084/jem.15.2.201. [DOI] [PMC free article] [PubMed] [Google Scholar]

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