Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1920 Jul 31;32(2):143–152. doi: 10.1084/jem.32.2.143

BLACKHEAD IN CHICKENS AND ITS EXPERIMENTAL PRODUCTION BY FEEDING EMBRYONATED EGGS OF HETERAKIS PAPILLOSA

Theobald Smith 1, H W Graybill 1
PMCID: PMC2128273  PMID: 19868435

Abstract

Feeding embryonated eggs of Heterakis papillosa to brooder chickens led to a disease of both ceca, characterized by the presence of a core consisting of fecal matter, coagulated blood, and emigrated cells from the mucosa. The walls of the ceca were thickened as a result of cell invasion and multiplication, invasion and multiplication of Amœba meleagridis or allied parasites, and more rarely hemorrhage and edema. The respective parts played by Heterakis papillosa and the protozoa in starting the lesions and the source of the protozoa remain to be defined. The invasion of the liver by the protozoa was insignificant.

Full Text

The Full Text of this article is available as a PDF (558.2 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Graybill H. W., Smith T. PRODUCTION OF FATAL BLACKHEAD IN TURKEYS BY FEEDING EMBRYONATED EGGS OF HETERAKIS PAPILLOSA. J Exp Med. 1920 Apr 30;31(5):647–655. doi: 10.1084/jem.31.5.647. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES