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. 1924 Feb 29;39(3):457–471. doi: 10.1084/jem.39.3.457

THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE

II. THE TOXIC EFFECT OF KILLED BACTERIA IN ADRENALECTOMIZED RATS.

W J M Scott 1
PMCID: PMC2128475  PMID: 19868857

Abstract

1. The resistance of rats to bacterial intoxication is greatly decreased after double adrenalectomy. 2. This decreased resistance is dependent upon a functional insufficiency of the adrenal cortex. 3. A dose of killed streptococci or staphylococci can be obtained that is invariably fatal to adrenalectomized rats, before hypertrophy of cortical accessories, but never kills control rats.

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Selected References

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  1. Scott W. J. INFLUENCE OF GLANDS WITH INTERNAL SECRETION ON THE RESPIRATORY EXCHANGE : IV. EFFECT OF SUPRARENAL INSUFFICIENCY IN CATS. J Exp Med. 1922 Jul 31;36(2):199–217. doi: 10.1084/jem.36.2.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Scott W. J. THE INFLUENCE OF THE ADRENAL GLANDS ON RESISTANCE : I. THE SUSCEPTIBILITY OF ADRENALECTOMIZED RATS TO MORPHINE. J Exp Med. 1923 Oct 31;38(5):543–560. doi: 10.1084/jem.38.5.543. [DOI] [PMC free article] [PubMed] [Google Scholar]

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