Abstract
Sera produced by immunization with crystalline oxyhemoglobin react species-specifically with hemoglobin solutions. Evidence is presented that in this reaction the hemoglobin itself is the active substance. Conversion of oxyhemoglobin into methemoglobin, carbon-monoxy hemoglobin, or cyanhemoglobin does not alter the response to the precipitating immune serum. Not only the hemoglobin of homologous species, but also that of other species causes inhibition in greater or less degree of the precipitin reaction.
Full Text
The Full Text of this article is available as a PDF (537.6 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ford W. W., Halsey J. T. Contributions to the Study of Hemagglutinins and Hemolysins. J Med Res. 1904 May;11(2):403–425. [PMC free article] [PubMed] [Google Scholar]
- Gay F. P., Robertson T. B. THE ANTIGENIC PROPERTIES OF GLOBIN CASEINATE. J Exp Med. 1913 May 1;17(5):535–541. doi: 10.1084/jem.17.5.535. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gay F. P., Robertson T. B. THE ANTIGENIC PROPERTIES OF GLOBIN CASEINATE. J Exp Med. 1913 May 1;17(5):535–541. doi: 10.1084/jem.17.5.535. [DOI] [PMC free article] [PubMed] [Google Scholar]