Abstract
It may be concluded that, under the conditions of the experiments: 1. Lymphocytes and large mononuclear cells can live and increase greatly in numbers in blood serum, while fibroblasts are not capable of doing so. 2. While living in serum, lymphocytes and large mononuclear cells manufacture and secrete substances which may be used as food material by the fibroblasts. 3. It is probable that lymphocytes and large mononuclear cells synthetize from the nitrogenous compounds contained in serum the substances which fibroblasts and epithelial cells require for their multiplication.
Full Text
The Full Text of this article is available as a PDF (509.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Carrel A. A METHOD FOR THE PHYSIOLOGICAL STUDY OF TISSUES IN VITRO. J Exp Med. 1923 Sep 30;38(4):407–418. doi: 10.1084/jem.38.4.407. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carrel A., Ebeling A. H. ACTION OF SERUM ON FIBROBLASTS IN VITRO. J Exp Med. 1923 May 31;37(6):759–765. doi: 10.1084/jem.37.6.759. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carrel A., Ebeling A. H. LEUCOCYTIC SECRETIONS. J Exp Med. 1922 Nov 30;36(6):645–659. doi: 10.1084/jem.36.6.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carrel A., Ebeling A. H. SURVIVAL AND GROWTH OF FIBROBLASTS IN VITRO. J Exp Med. 1923 Oct 31;38(5):487–497. doi: 10.1084/jem.38.5.487. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carrel A. GROWTH-PROMOTING FUNCTION OF LEUCOCYTES. J Exp Med. 1922 Sep 30;36(4):385–391. doi: 10.1084/jem.36.4.385. [DOI] [PMC free article] [PubMed] [Google Scholar]