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. 1924 Nov 30;40(6):733–742. doi: 10.1084/jem.40.6.733

EXPERIMENTAL PRODUCTION OF PNEUMOCOCCUS PNEUMONIA IN MICE BY THE INHALATION METHOD

Ernest G Stillman 1, Arnold Branch 1
PMCID: PMC2128601  PMID: 19868954

Abstract

1. Non-immune mice which are alcoholized and die of septicemia following exposure to a spray of virulent pneumococci rarely show any localization of infection in the lung. 2. Mice which have been partially immunized by previous inhalations of living or killed pneumococci and which while alcoholized are exposed to an atmosphere of virulent pneumococci often develop a pneumococcus lobar pneumonia. 3. Mice which have been rendered relatively immune to one type of pneumococcus may frequently develop lobar pneumonia after the inhalation of pneumococci of another type.

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Selected References

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  1. Blake F. G., Cecil R. L. STUDIES ON EXPERIMENTAL PNEUMONIA : I. PRODUCTION OF PNEUMOCOCCUS LOBAR PNEUMONIA IN MONKEYS. J Exp Med. 1920 Mar 31;31(4):403–443. doi: 10.1084/jem.31.4.403. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Branch A., Stillman E. G. PATHOLOGY OF EXPERIMENTAL PNEUMOCOCCUS PNEUMONIA IN MICE. J Exp Med. 1924 Nov 30;40(6):743–752. doi: 10.1084/jem.40.6.743. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Jones F. S. THE INFLUENCE OF RESISTANCE ON THE CHARACTER OF DISEASE IN EXPERIMENTAL RESPIRATORY INFECTION. J Exp Med. 1924 Apr 30;39(5):725–743. doi: 10.1084/jem.39.5.725. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kline B. S., Winternitz M. C. STUDIES UPON EXPERIMENTAL PNEUMONIA IN RABBITS : VII. THE PRODUCTION OF LOBAR PNEUMONIA. J Exp Med. 1915 Apr 1;21(4):304–310. doi: 10.1084/jem.21.4.304. [DOI] [PMC free article] [PubMed] [Google Scholar]

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