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The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1924 Oct 31;40(5):619–625. doi: 10.1084/jem.40.5.619

THE INFLUENCE OF THE SUPRARENAL GLAND ON THE THYMUS

II. DIRECT EVIDENCE OF REGENERATION OF THE INVOLUTED THYMUS FOLLOWING DOUBLE SUPRARENALECTOMY IN THE RAT.

Henry L Jaffe 1
PMCID: PMC2128608  PMID: 19868945

Abstract

1. Regeneration of involuted thymuses of old rats follows double suprarenalectomy in this species with great constancy. 2. Partial thymectomy alone does not induce compensatory secondary hyperplasia in involuting glands. 3. Regeneration of the thymus following suprarenalectomy would appear to be completed in most rats in about 2 weeks; and it probably begins in the medulla.

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Selected References

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  1. Jaffe H. L. THE INFLUENCE OF THE SUPRARENAL GLAND ON THE THYMUS : I. REGENERATION OF THE THYMUS FOLLOWING DOUBLE SUPRARENALECTOMY IN THE RAT. J Exp Med. 1924 Aug 31;40(3):325–342. doi: 10.1084/jem.40.3.325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Marine D., Manley O. T., Baumann E. J. THE INFLUENCE OF THYROIDECTOMY, GONADECTOMY, SUPRARENALECTOMY, AND SPLENECTOMY ON THE THYMUS GLAND OF RABBITS. J Exp Med. 1924 Sep 30;40(4):429–443. doi: 10.1084/jem.40.4.429. [DOI] [PMC free article] [PubMed] [Google Scholar]

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