Abstract
In the present study rubella HI antibodies were determined in cases of congenital malformation and bad obstetric history to determine the role of rubella in such cases in India, as it has been reported to be rare in Japan in contrast to Western countries. The incidence of antibodies was statistically significant in cases of congenital eye, C.N.S., visceral and miscellaneous malformations and cases of spontaneous abortion and still-birth compared with controls of matching age groups. This is further supported by the demonstration of IgM antibodies in seven cases of congenital malformations and ten cases of spontaneous abortion. Our findings show that congenital rubella is not rare in India.
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Selected References
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- Banatvala J. E., Best J. M., Kennedy E. A., Smith E. E., Spence M. E. A serological method for demonstrating recent infection by rubella virus. Br Med J. 1967 Jul 29;3(5560):285–286. doi: 10.1136/bmj.3.5560.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Best J. M., Banatvala J. E., Bowen J. M. New Japanese rubella vaccine: comparative trials. Br Med J. 1974 Jul 27;3(5925):221–224. doi: 10.1136/bmj.3.5925.221. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Best J. M., Banatvala J. E., Watson D. Serum IgM and IgG responses in postnatally acquired rubella. Lancet. 1969 Jul 12;2(7611):65–68. doi: 10.1016/s0140-6736(69)92386-1. [DOI] [PubMed] [Google Scholar]
- Cooper L. Z., Krugman S. Diagnosis and management: congenital rubella. Pediatrics. 1966 Feb;37(2):335–338. [PubMed] [Google Scholar]
- Gumpel S. M., Hayes K., Dudgeon J. A. Congenital perceptive deafness: role of intrauterine rubella. Br Med J. 1971 May 8;2(5757):300–304. doi: 10.1136/bmj.2.5757.300. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Halonen P. E., Ryan J. M., Stewart J. A. Rubella hemagglutinin prepared with alkaline extraction of virus grown in suspension culture of BHK-21 cells. Proc Soc Exp Biol Med. 1967 May;125(1):162–167. doi: 10.3181/00379727-125-32038. [DOI] [PubMed] [Google Scholar]
- Honeyman M. C., Menser M. A. Ethnicity is a significant factor in the epidemiology of rubella and Hodgkin's disease. Nature. 1974 Oct 4;251(5474):441–442. doi: 10.1038/251441a0. [DOI] [PubMed] [Google Scholar]
- Kono R., Hayakawa Y., Hibi M., Ishii K. Experimental vertical transmission of rubella virus in rabbits. Lancet. 1969 Feb 15;1(7590):343–347. doi: 10.1016/s0140-6736(69)91301-4. [DOI] [PubMed] [Google Scholar]
- Mathur A., Chaturvedi U. C., Mehrotra R. M. Serological study for the prevalence of rubella at Lucknow. Indian J Med Res. 1974 Feb;62(2):307–312. [PubMed] [Google Scholar]
- Potter J. E., Banatvala J. E., Best J. M. Interferon studies with Japanese and U.S. rubella virus strains. Br Med J. 1973 Jan 27;1(5847):197–199. doi: 10.1136/bmj.1.5847.197. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rawls W. E., Melnick J. L., Bradstreet C. M., Bailey M., Ferris A. A., Lehmann N. I., Nagler F. P., Furesz J., Kono R., Ohtawara M. WHO collaborative study on the sero-epidemiology of rubella. Bull World Health Organ. 1967;37(1):79–88. [PMC free article] [PubMed] [Google Scholar]
