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. 1979 Feb;82(1):31–40. doi: 10.1017/s0022172400025444

The increasing isolation of Serratia species from clinical specimens.

H J Brooks, T J Chambers, S Tabaqchali
PMCID: PMC2130121  PMID: 762403

Abstract

A 14-month survey was undertaken in a diagnostic bacteriology laboratory to determine the incidence of Serratia spp. in routine clinical specimens. Gram-negative organisms with enterobacteria-like colonies were tested by a simple screening procedure. Fifty-eight strains of S. marcescens and two strains of S. liquefaciens were isolated from 59 patients. The strains were usually non-pigmented and exhibited multiple antibiotic resistance. Serotyping and determination of bacteriocine sensitivity patterns revealed that the majority of infections were sporadic, although episodes of cross-infection did occur. S. marcescens was considered to contribute significantly to morbidity and mortality in 53% of patients and appears to be of increasing importance in hospital-acquired infections.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderhub B., Pitt T. L., Erdman Y. J., Willcox W. R. A comparison of typing methods for Serratia marcescens. J Hyg (Lond) 1977 Aug;79(1):89–102. doi: 10.1017/s0022172400052888. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ball A. P., McGhie D., Geddes A. M. Serratia marcescens in a general hospital. Q J Med. 1977 Jan;46(181):63–71. [PubMed] [Google Scholar]
  3. Black W. A., Hatch L. A., Binnie P., Newberry J. Proceedings: Serratia marcescens infection in a general hospital. J Clin Pathol. 1973 Dec;26(12):984–985. doi: 10.1136/jcp.26.12.984-d. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Black W. A., Hodgson R. Search for Serratia. J Clin Pathol. 1971 Jul;24(5):444–448. doi: 10.1136/jcp.24.5.444. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Black W. A., Pollock A., Batchelor E. L. Fatal transfusion reaction due to Serratia marcescens. J Clin Pathol. 1967 Nov;20(6):883–886. doi: 10.1136/jcp.20.6.883. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Cardos S. F., Florman A. L., Simberkoff M. S., Lanier L. Serratia marcescens: use of detailed characterization of strains to evaluate an increase of isolates in an intensive care unit. Am J Med Sci. 1973 Dec;266(6):447–452. [PubMed] [Google Scholar]
  7. Clayton E., Von Graevenitz A. Nonpigmented Serratia marcescens. JAMA. 1966 Sep 26;197(13):1059–1064. [PubMed] [Google Scholar]
  8. Davis J. T., Foltz E., Blakemore W. S. Serratia marcescens. A pathogen of increasing clinical importance. JAMA. 1970 Dec 21;214(12):2190–2192. doi: 10.1001/jama.214.12.2190. [DOI] [PubMed] [Google Scholar]
  9. Dodson W. H. Serratia marcescens septicemia. Arch Intern Med. 1968 Feb;121(2):145–150. [PubMed] [Google Scholar]
  10. GALE D., SONNENWIRTH A. C. Frequent human isolation of Serratia marcescens. Bacteriological and pathogenicity studies of twelve strains of S. marcescens recovered from nine patients during a six-month period. Arch Intern Med. 1962 Apr;109:414–421. doi: 10.1001/archinte.1962.03620160040006. [DOI] [PubMed] [Google Scholar]
  11. Hedges R. W., Rodriguez-Lemoine V., Datta N. R factors from Serratia marcescens. J Gen Microbiol. 1975 Jan;86(1):88–92. doi: 10.1099/00221287-86-1-88. [DOI] [PubMed] [Google Scholar]
  12. LANCASTER L. J. Role of Serratia species in urinary tract infections. Arch Intern Med. 1962 May;109:536–539. doi: 10.1001/archinte.1962.03620170034005. [DOI] [PubMed] [Google Scholar]
  13. MCCRACKEN A. W., LIPSCOMB F. E. SERRATIA MARCESCENS INFECTION COMPLICATING PERITONEAL DIALYSIS. Br Med J. 1965 Jun 12;1(5449):1536–1537. doi: 10.1136/bmj.1.5449.1536. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Maki D. G., Hennekens C. G., Phillips C. W., Shaw W. V., Bennett J. V. Nosocomial urinary tract infection with Serratia marcescens: an epidemiologic study. J Infect Dis. 1973 Nov;128(5):579–587. doi: 10.1093/infdis/128.5.579. [DOI] [PubMed] [Google Scholar]
  15. McCormack R. C., Kunin C. M. Control of a single source nursery epidemic due to Serratia marcescens. Pediatrics. 1966 May;37(5):750–755. [PubMed] [Google Scholar]
  16. Meltz D. J., Grieco M. H. Characteristics of Serratia marcescens pneumonia. Arch Intern Med. 1973 Sep;132(3):359–364. [PubMed] [Google Scholar]
  17. Meyer R. D., Lewis R. P., Halter J., White M. Gentamicin-resistant Pseudomonas aeruginosa and Serratia marcescens in a general hospital. Lancet. 1976 Mar 13;1(7959):580–583. doi: 10.1016/s0140-6736(76)90370-6. [DOI] [PubMed] [Google Scholar]
  18. Price K. E., DeFuria M. D., Pursiano T. A. Amikacin, an aminoglycoside with marked activity against antibiotic-resistant clinical isolates. J Infect Dis. 1976 Nov;134(Suppl):S249–S261. doi: 10.1093/infdis/135.supplement_2.s249. [DOI] [PubMed] [Google Scholar]
  19. Schaefler S., Winter J., Catelli A., Greene J., Toharski B. Specific distribution of R factors in Serratia marcescens strains isolated from hospital infections. Appl Microbiol. 1971 Sep;22(3):339–343. doi: 10.1128/am.22.3.339-343.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Schreier J. B. Modification of deoxyribonuclease test medium for rapid identification of Serratia marcescens. Am J Clin Pathol. 1969 Jun;51(6):711–716. doi: 10.1093/ajcp/51.6.711. [DOI] [PubMed] [Google Scholar]
  21. TAYLOR G., KEANE P. M. Cross-infection with Serratia marcescens. J Clin Pathol. 1962 Mar;15:145–147. doi: 10.1136/jcp.15.2.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Tabaqchali S., Chambers T. J., Brooks H. J. Serratia marcescens in hospital practice. Lancet. 1977 Feb 5;1(8006):306–307. doi: 10.1016/s0140-6736(77)91851-7. [DOI] [PubMed] [Google Scholar]
  23. Traub W. H. Continued surveillance of Serratia marcescens infections by bacteriocin typing: investigation of two outbreaks of cross-infection in an intensive care unit. Appl Microbiol. 1972 May;23(5):982–985. doi: 10.1128/am.23.5.982-985.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Whitby J. L., Blair J. N., Rampling A. Cross-infection with Serratia marcescens in an intensive-therapy unit. Lancet. 1972 Jul 15;2(7768):127–129. doi: 10.1016/s0140-6736(72)91612-1. [DOI] [PubMed] [Google Scholar]
  25. Wilfert J. N., Barrett F. F., Kass E. H. Bacteremia due to serratia marcescens. N Engl J Med. 1968 Aug 8;279(6):286–289. doi: 10.1056/NEJM196808082790604. [DOI] [PubMed] [Google Scholar]
  26. Wilkowske C. J., Washington J. A., 2nd, Martin W. J., Ritts R. E., Jr Serratia marcescens. Biochemical characteristics, antibiotic susceptibility patterns, and clinical significance. JAMA. 1970 Dec 21;214(12):2157–2162. doi: 10.1001/jama.214.12.2157. [DOI] [PubMed] [Google Scholar]

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