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. 1979 Apr;82(2):195–205. doi: 10.1017/s0022172400025614

Nosocomial klebsiellas. II. Transfer in a hospital ward.

M J Haverkorn, M F Michel
PMCID: PMC2130137  PMID: 429786

Abstract

During a 6-month period an epidemiological survey of the carriage of Klebsiella was conducted in a hospital ward where no outbreak of nosocomial infection occurred. In this endemic situation the regular sampling of several sites of patients, members of the nursing staff, and the environment, and the biotyping of Klebsiella made it possible to analyse the patterns of transmission between sites. There was abundant evidence for striking transmission of Klebsiella between the throat, hands, and faeces of patients. Transmission between patients seemed to be mainly through hands. The role of nurses' hands in transmission was not evident from this survey, probably due to the relatively long interval (a week) between samplings. Through the hands of patients, wash stands and the surrounding floor were contaminated with Klebsiella. The biotyping of Klebsiella facilitated the epidemiological analysis of the results.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burke J. P., Ingall D., Klein J. O., Gezon H. M., Finland M. Proteus mirabilis infections in a hospital nursery traced to a human carrier. N Engl J Med. 1971 Jan 21;284(3):115–121. doi: 10.1056/NEJM197101212840301. [DOI] [PubMed] [Google Scholar]
  2. Casewell M. W., Dalton M. T., Webster M., Phillips I. Gentamicin-resistant Klebsiella aerogenes in a urological ward. Lancet. 1977 Aug 27;2(8035):444–446. doi: 10.1016/s0140-6736(77)90621-3. [DOI] [PubMed] [Google Scholar]
  3. Cooke E. M., Kumar P. J., Shooter R. A., Rousseau S. A., Foulkes A. L. Hospital food as a possible source of Escherichia coli in patients. Lancet. 1970 Feb 28;1(7644):436–437. doi: 10.1016/s0140-6736(70)90830-5. [DOI] [PubMed] [Google Scholar]
  4. Edwards L. D., Cross A., Levin S., Landau W. Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to many antimicrobials. Am J Clin Pathol. 1974 Jan;61(1):41–46. doi: 10.1093/ajcp/61.1.41. [DOI] [PubMed] [Google Scholar]
  5. Eisenach K. D., Reber R. M., Eitzman D. V., Baer H. Nosocomial infections due to kanamycin-resistant, (R)-factor carrying enteric organisms in an intensive care nursery. Pediatrics. 1972 Sep;50(3):395–402. [PubMed] [Google Scholar]
  6. Finland M. Changing ecology of bacterial infections as related to antibacterial therapy. J Infect Dis. 1970 Nov;122(5):419–431. doi: 10.1093/infdis/122.5.419. [DOI] [PubMed] [Google Scholar]
  7. Fontaine T. D., 3rd, Hoadley A. W. Transferable drug resistance associated with coliforms isolated from hospital and domestic sewage. Health Lab Sci. 1976 Oct;13(4):238–245. [PubMed] [Google Scholar]
  8. Grieble H. G., Bird T. J., Nidea H. M., Miller C. A. Chute-hydropulping waste disposal system: a reservoir of enteric bacilli and pseudomonas in a modern hospital. J Infect Dis. 1974 Dec;130(6):602–607. doi: 10.1093/infdis/130.6.602. [DOI] [PubMed] [Google Scholar]
  9. HARVEY H. S., DUNLAP M. B. Upper respiratory flora of husbands and wives: a comparison. N Engl J Med. 1960 May 12;262:976–977. doi: 10.1056/NEJM196005122621907. [DOI] [PubMed] [Google Scholar]
  10. Haverkorn M. L., Michel M. F. Nosocomial klebsiellas. I. Colonization of hospitalized patients. J Hyg (Lond) 1979 Apr;82(2):177–193. doi: 10.1017/s0022172400025602. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Johanson W. G., Jr, Pierce A. K., Sanford J. P., Thomas G. D. Nosocomial respiratory infections with gram-negative bacilli. The significance of colonization of the respiratory tract. Ann Intern Med. 1972 Nov;77(5):701–706. doi: 10.7326/0003-4819-77-5-701. [DOI] [PubMed] [Google Scholar]
  12. Knittle M. A., Eitzman D. V., Baer H. Role of hand contamination of personnel in the epidemiology of gram-negative nosocomial infections. J Pediatr. 1975 Mar;86(3):433–437. doi: 10.1016/s0022-3476(75)80980-2. [DOI] [PubMed] [Google Scholar]
  13. Lowbury E. J., Thom B. T., Lilly H. A., Babb J. R., Whittall K. Sources of infection with Pseudomonas aeruginosa in patients with tracheostomy. J Med Microbiol. 1970 Feb;3(1):39–56. doi: 10.1099/00222615-3-1-39. [DOI] [PubMed] [Google Scholar]
  14. Marsh P. D., Selwyn S. Studies on antagonism between human skin bacteria. J Med Microbiol. 1977 May;10(2):161–169. doi: 10.1099/00222615-10-2-161. [DOI] [PubMed] [Google Scholar]
  15. McBride M. E., Duncan W. C., Knox J. M. The environment and the microbial ecology of human skin. Appl Environ Microbiol. 1977 Mar;33(3):603–608. doi: 10.1128/aem.33.3.603-608.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. McGowan J. E., Jr, Finland M. Infection and antibiotic usage at Boston City Hospital: changes in prevalence during the decade 1964-1973. J Infect Dis. 1974 Apr;129(4):421–428. doi: 10.1093/infdis/129.4.421. [DOI] [PubMed] [Google Scholar]
  17. Mendes M. F., Lynch D. J. A bacteriological survey of washrooms and toilets. J Hyg (Lond) 1976 Apr;76(2):183–190. doi: 10.1017/s002217240005508x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Pettit F., Lowbury E. J. Survival of wound pathogens under different environmental conditions. J Hyg (Lond) 1968 Sep;66(3):393–406. doi: 10.1017/s0022172400041267. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Rose H. D., Babcock J. B. Colonization of intensive care unit patients with gram-negative bacilli. Am J Epidemiol. 1975 Jun;101(6):495–501. doi: 10.1093/oxfordjournals.aje.a112120. [DOI] [PubMed] [Google Scholar]
  20. Rosenthal S., Tager I. B. Prevalence of gram-negative rods in the normal pharyngeal flora. Ann Intern Med. 1975 Sep;83(3):355–357. doi: 10.7326/0003-4819-83-3-355. [DOI] [PubMed] [Google Scholar]
  21. Salzman T. C., Clark J. J., Klemm L. Hand contamination of personnel as a mechanism of cross-infection in nosocomial infections with antibiotic-resistant Escherichia coli and Klebsiella-Aerobacter. Antimicrob Agents Chemother (Bethesda) 1967;7:97–100. [PubMed] [Google Scholar]
  22. Schaberg D. R., Weinstein R. A., Stamm W. E. Epidemics of nosocomial urinary tract infection caused by multiply resistant gram-negative bacilli: epidemiology and control. J Infect Dis. 1976 Mar;133(3):363–366. doi: 10.1093/infdis/133.3.363. [DOI] [PubMed] [Google Scholar]
  23. Selden R., Lee S., Wang W. L., Bennett J. V., Eickhoff T. C. Nosocomial klebsiella infections: intestinal colonization as a reservoir. Ann Intern Med. 1971 May;74(5):657–664. doi: 10.7326/0003-4819-74-5-657. [DOI] [PubMed] [Google Scholar]
  24. Shooter R. A. Bowel colonization of hospital patients by Pseudomonas aeruginosa and Escherichia coli. Proc R Soc Med. 1971 Sep;64(9):989–990. [PMC free article] [PubMed] [Google Scholar]
  25. Sprunt K., Redman W., Leidy G. Antibacterial effectiveness of routine hand washing. Pediatrics. 1973 Aug;52(2):264–271. [PubMed] [Google Scholar]

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