Skip to main content
The Journal of Hygiene logoLink to The Journal of Hygiene
. 1972 Dec;70(4):611–617. doi: 10.1017/s0022172400022476

The mechanism of cross-protection afforded by dengue virus against West Nile virus in hamsters*

Winston H Price, Inderjit S Thind
PMCID: PMC2130280  PMID: 4509639

Abstract

The protection afforded by similar concentrations of different dengue virus serotypes against a subsequent challenge of West Nile virus was studied in hamsters. The New Guinea C strain of dengue 2 virus gave the best protection. It was found that the anamnestic neutralizing antibody response induced by the challenge West Nile virus against West Nile virus in hamsters, previously immunized with dengue 2 virus, might play a major role in the cross-protection observed in this system.

Full text

PDF
611

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CASALS J. RELATIONSHIPS AMONG ARTHROPOD-BORNE ANIMAL VIRUSES DETERMINED BY CROSS-CHALLENGE TESTS. Am J Trop Med Hyg. 1963 Jul;12:587–596. doi: 10.4269/ajtmh.1963.12.587. [DOI] [PubMed] [Google Scholar]
  2. IMAM I. Z., HAMMON W. M. Challenge of hamsters with Japanese B, St. Louis and Murray Valley encephalitis viruses after immunization by West Nile infection plus specific vaccine. J Immunol. 1957 Sep;79(3):243–252. [PubMed] [Google Scholar]
  3. Price W. H., Thind I. S. Protection against West Nile virus induced by a previous injection with dengue virus. Am J Epidemiol. 1971 Dec;94(6):596–607. doi: 10.1093/oxfordjournals.aje.a121358. [DOI] [PubMed] [Google Scholar]
  4. Sather G. E., Hammon W. M. Protection against St. Louis encephalitis and West Nile arboviruses by previous dengue virus (types 1-4) infection. Proc Soc Exp Biol Med. 1970 Nov;135(2):573–578. doi: 10.3181/00379727-135-35098a. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press

RESOURCES